Med Spas in Port St. Lucie, FL

Find 15 med spas in Port St. Lucie, Florida. Browse ratings, opening hours and directions below, or see nearby cities in Florida.

15med spas
5.0★Enchanted Skin Studio
14publish hours
4full profiles

Port St. Lucie, Florida has 15 med spas. Enchanted Skin Studio is the highest-rated, with a 5-star rating based on 106 reviews. Four other med spas also hold 5-star ratings: Luxe Wellness Med Spa (43 reviews), Skin Healer Luxury Aesthetics (59 reviews), and Soleil Med Spa + Wellness (43 reviews). Several others are rated 4.9 stars, including Refresh – Aesthetics & Wellness (751 reviews), Port St. Lucie Medical Wellness (552 reviews), Sejour Medical Aesthetics – Port St Lucie (189 reviews), USA Aesthetics (121 reviews), LifeWell MD (30 reviews), and Sejour Medical Aesthetics.

Thirteen of the 15 med spas in Port St. Lucie post their hours online. These include Enchanted Skin Studio, Luxe Wellness Med Spa, PSL Laser and Aesthetics, Skin Healer Luxury Aesthetics, Soleil Med Spa + Wellness, VIPS MedSpa + CoolSculpting Center – Port Saint Lucie West, LifeWell MD, Port St. Lucie Medical Wellness, Refresh – Aesthetics & Wellness, Sejour Medical Aesthetics – Port St Lucie, and USA Aesthetics. Blissful Contour Med Spa in Port St. Lucie, Florida does not list hours online.

Map of Med Spas in Port St. Lucie

Advanced Dermatology and Cosmetic Surgery
4.7(962)

11474 SW Vlg Pkwy, Port St. Lucie, FL 34987

Mon–Fri 8 AM–5 PM
(772) 318-4945 Website

View details Directions
Refresh – Aesthetics & Wellness
4.9(751)

1430 St Lucie W Blvd #101, Port St. Lucie, FL 34986

Mon–Wed 9 AM–5:30 PM
Thu 9 AM–9 PM
Fri 9 AM–5:30 PM
(772) 213-9713 Website

View details Directions
Port St. Lucie Medical Wellness
4.9(552)

702 SW Port St Lucie Blvd, Port St. Lucie, FL 34953

Mon–Thu 9 AM–5 PM
Fri 8 AM–5 PM
Sat 9 AM–2 PM
(772) 207-0080 Website

View details Directions
New Radiance Cosmetic Centers – Port St. Lucie
4.8(543)

318 NW Bethany Dr, Port St. Lucie, FL 34986

Mon 9 AM–4 PM
Tue 9 AM–6 PM
Wed–Sat 9 AM–4 PM
(772) 266-5795 Website

View details Directions
Sejour Medical Aesthetics – Port St Lucie
4.9(189)

8976 S U.S. Hwy 1, Port St. Lucie, FL 34952

Tue–Fri 10 AM–5 PM
Sat 10 AM–3 PM

(772) 800-7784 Website

Directions
SkinRise Wellness & MedSpa
4.7(183)

451 SW Bethany Dr #100, Port St. Lucie, FL 34986

Mon–Thu 10 AM–7 PM
Fri 10 AM–4 PM
Sun 11 AM–7 PM

(772) 204-2811 Website

Directions
USA Aesthetics
4.9(121)

10190 SW Vlg Pkwy Ste 106, Port St. Lucie, FL 34987

Mon–Thu 9 AM–6 PM

(772) 230-1000 Website

Directions
Enchanted Skin Studio
5.0(106)

Oasis Salon Suites, 374 SW Prima Vista Blvd Ste 3, Port St. Lucie, FL 34983

Tue 10 AM–5 PM
Wed 10 AM–6:30 PM
Thu–Fri 10 AM–5 PM
Sat 9 AM–4:30 PM

(772) 259-5634 Website

Directions
Skin Healer Luxury Aesthetics
5.0(59)

1763 St Lucie W Blvd Ste 113, Port St. Lucie, FL 34986

Mon–Sat 9 AM–6 PM

(772) 292-9199 Website

Directions
Luxe Wellness Med Spa
5.0(43)

10377 S U.S. Hwy 1 STE 101, Port St. Lucie, FL 34952

Mon–Fri 9 AM–5 PM

(772) 971-5867 Website

Directions
Soleil Med Spa + Wellness
5.0(43)

3241 SW Port St Lucie Blvd, Port St. Lucie, FL 34953

Tue–Fri 10 AM–6 PM
Sat 9 AM–3 PM

(772) 356-2500 Website

Directions
LifeWell MD
4.9(30)

549 NW Lake Whitney Pl Ste 103, Port St. Lucie, FL 34986

Mon–Fri 8 AM–5 PM

(561) 210-9999 Website

Directions
PSL Laser and Aesthetics
5.0(21)

1967 SE Port St Lucie Blvd, Port St. Lucie, FL 34952

Mon–Fri 9 AM–6 PM
Sat 9 AM–12 PM

(772) 335-3110 Website

Directions
VIPS MedSpa + CoolSculpting Center – Port Saint Lucie West
5.0(6)

291 NW Peacock Blvd Ste 103, Port St. Lucie, FL 34986

Mon 9 AM–4 PM
Tue–Fri 9 AM–5 PM

(772) 205-6329 Website

Directions
Blissful Contour Med Spa in Port St. Lucie, Florida
5.0(4)

8491 S U.S. Hwy 1, Port St. Lucie, FL 34952

(772) 202-8441

Directions

Mon–Fri	8 AM–5 PM

Mon–Wed	9 AM–5:30 PM
Thu	9 AM–9 PM
Fri	9 AM–5:30 PM

Mon–Thu	9 AM–5 PM
Fri	8 AM–5 PM
Sat	9 AM–2 PM

Mon	9 AM–4 PM
Tue	9 AM–6 PM
Wed–Sat	9 AM–4 PM

Tue–Fri	10 AM–5 PM
Sat	10 AM–3 PM

Mon–Thu	10 AM–7 PM
Fri	10 AM–4 PM
Sun	11 AM–7 PM

Mon–Thu	9 AM–6 PM

Tue	10 AM–5 PM
Wed	10 AM–6:30 PM
Thu–Fri	10 AM–5 PM
Sat	9 AM–4:30 PM

Mon–Sat	9 AM–6 PM

Mon–Fri	9 AM–5 PM

Tue–Fri	10 AM–6 PM
Sat	9 AM–3 PM

Mon–Fri	8 AM–5 PM

Mon–Fri	9 AM–6 PM
Sat	9 AM–12 PM

Mon	9 AM–4 PM
Tue–Fri	9 AM–5 PM

Nearby Cities

Frequently Asked Questions

How many med spas are there in Port St. Lucie, FL?

There are 15 med spas listed in Port St. Lucie, FL: Advanced Dermatology and Cosmetic Surgery, Blissful Contour Med Spa in Port St. Lucie, Florida, Enchanted Skin Studio, LifeWell MD, Luxe Wellness Med Spa and 10 more.

Which med spa in Port St. Lucie, FL is the highest rated?

Enchanted Skin Studio has the highest rating in our directory for Port St. Lucie, FL: 5★ from 106 reviews.

Which med spas in Port St. Lucie, FL have posted opening hours?

14 of the 15 med spas in Port St. Lucie, FL publish opening hours: Advanced Dermatology and Cosmetic Surgery, Enchanted Skin Studio, LifeWell MD, Luxe Wellness Med Spa, New Radiance Cosmetic Centers – Port St. Lucie and 9 more.

What is the population of Port St. Lucie, FL?

Port St. Lucie has a population of 268,062 (U.S. Census Bureau, 2025 estimate).

Med Spas in Port St. Lucie, FL

Map of Med Spas in Port St. Lucie

Advanced Dermatology and Cosmetic Surgery

Refresh – Aesthetics & Wellness

Port St. Lucie Medical Wellness

New Radiance Cosmetic Centers – Port St. Lucie

Sejour Medical Aesthetics – Port St Lucie

SkinRise Wellness & MedSpa

USA Aesthetics

Enchanted Skin Studio

Skin Healer Luxury Aesthetics

Luxe Wellness Med Spa

Soleil Med Spa + Wellness

LifeWell MD

PSL Laser and Aesthetics

VIPS MedSpa + CoolSculpting Center – Port Saint Lucie West

Blissful Contour Med Spa in Port St. Lucie, Florida

Nearby Cities

Frequently Asked Questions